Autophagic Flux: Is p62 a Good Indicator of Autophagy Degradation?

Merek: p62 cim

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p62 cim  , @ Password Show Your password is Opposing regulation of the STING pathway in hepatic stellate cells by NBR1 and p62 determines the  Our results show that using such mechanisms, p62 filaments can be critical for cargo uptake in autophagy and are an integral part of phase-separated p62 bodies

p62 cim p62 serves as an adaptor protein for selective autophagy: when selective autophagic cargos such as damaged mitochondria appear in the cytoplasm, they are p62 provides dual, reciprocal enhancing protection to RPE cells from environmental stress induced protein misfolding and aggregation

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