Impacts on the Aggresome-autophagy pathway and Microtubule

p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria autophagy pathway p62

Accumulation of p62 can activate NRF2 by a non-canonical pathway The p62 protein competitively binds to Kelchlike-ECH-associated

p62cim p62 · PINK1Parkin · ULK · Cell CycleDNA Damage · Antifolate · APC · ATF6 · ATMATR Pathway: Cell CycleDNA Damage; Apoptosis; Target: DNARNA Synthesis; The Keap1-Nrf2 system and autophagy are both involved in the oxidative-stress response, metabolic pathways, and innate immunity, and dysregulation of these Autophagy receptors, including p62, target invading intracellular pathogens to the autophagy pathway for degradation p62 is able to co

g2g56 สล็อต Upon binding to its ligand, p62 acts as a modulator of macroautophagy, inducing autophagosome biogenesis Through these dual functions, cells