Nrf2-p62 autophagy pathway and its response to oxidative stress in
Nrf2-p62 autophagy pathway and its response to oxidative stress in
p62 is a receptor for cargo destined to be degraded by autophagy, including ubiquitinated protein aggregates destined for clearance The p62 protein is able to
Accumulation of p62 can activate NRF2 by a non-canonical pathway The p62 protein competitively binds to Kelchlike-ECH-associated
ทาง เข้า p62 ทาง เข้า believed that, in neural stem cells , Atg7 and P62 might inhibit the G1 to S phase of the cell cycle through the autophagy pathway, thus
p62com The removal of abnormal proteins is primarily done by the ubiquitin–proteasome system , the major protein degradation pathway in the cell
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